Sarma Mutturi, Principal Scientist, CSIR-CFTRI
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Publications

Journal Articles

  1. Tissopi, T., Mistry, D., Ranjan, R., Upreti, R., Kumar, S., Kapoor, M., & Mutturi, S. (2025). Role of Glu720 mutation in transglycosylating α-glucosidase derived from aspergillus neoniger NCIM 1400. International Journal of Biological Macromolecules, 145644. https://doi.org/10.1016/j.ijbiomac.2025.145644
  2. Patra, P. A., Palakkandi, D., Gunturu, R., Mutturi, S., & Subban, N. (2025). Cyanidin-3-O-sambubioside isolation by preparative HPLC from kokum fruit rind and evaluation of SARS-CoV-2 main protease inhibition by in silico and in vitro studies. Food Bioscience, 68, 106586. https://doi.org/10.1016/j.fbio.2025.106586
  3. Patra, P. A., Palakkandi, D., Krishnegowda, A. K., Vijayarengan, M., Mutturi, S., Linganna, S., & Nagarajan, S. (2025). Flash chromatographic isolation of garcinol and isogarcinol from Garcinia indica Choisy (kokum) fruit and evaluation of their potential antibiofilm activity. Microbial Pathogenesis, 198, 107127. https://doi.org/10.1016/j.micpath.2024.107127
  4. Nellikka, A., Cheruvari, A., Vasu, P., Mutturi, S., & Rajagopal, K. (2024). Bifidobacterium adolescentis is resistant to pyrazinamide, isoniazid, and streptomycin. Scientific Reports, 14(1), 29562. https://doi.org/10.1038/s41598-024-78095-x
  5. Abdulla, A., Gupta, N., & Mutturi, S. (2024). Engineering of Saccharomyces cerevisiae towards synthesis of linalool using linalool synthase from Magnolia champaca. Biochemical Engineering Journal, 109477. https://doi.org/10.1016/j.bej.2024.109477
  6. Singh, A., Rajoriya, D., Obalesh, I. S., Prashantha, K. H., Chaudhari, S. R., Mutturi, S., … & Eligar, S. M. (2024). Arabinoxylan from pearl millet bran: Optimized extraction, structural characterization, and its bioactivities. International Journal of Biological Macromolecules, 135247. https://doi.org/10.1016/j.ijbiomac.2024.135247
  7. Amsaraj, R., Ranjan, R., Rachaiah, B. P., & Mutturi, S. (2024). Multi-instrument spectroscopic study for authentication of curcumin content in commercial turmeric powders using machine learning algorithms. Journal of Food Composition and Analysis, 134, 106543. https://doi.org/10.1016/j.jfca.2024.106543
  8. Karnat, S. R., Sarma Mutturi., & Somashekar, D. (2024). Study of changes in functional properties of fermented Idli batter during storage under different temperature conditions. Food and Humanity, 3, 100377. https://doi.org/10.1016/j.foohum.2024.100377
  9. Hari Prasad BR, Amrutha Kala AL, Sarma Mutturi, Asha Martin. “Comprehensive quality evaluation of Indian chili powder using physiochemical indicators coupled with multivariate analysis.” Journal of Food Composition and Analysis 133 (2024) 106472, https://doi.org/10.1016/j.jfca.2024.106472
  10. Drishya PK, Prachi AP, Anil Kumar L, Shivakumar L, Sarma Mutturi, Nagarajan S. “A facile microwave assisted synthesis of thymohydroquinone with antibiofilm properties against Salmonella typhi and Listeria monocytogenes.” Food Bioscience (2024): 60, 104372. https://doi.org/10.1016/j.fbio.2024.104372
  11. Peerzade, Ishrat Jahan, Sarma Mutturi, and Prakash M. Halami. “Improved production of RNA-inhibiting antimicrobial peptide by Bacillus licheniformis MCC 2514 facilitated by a genetic algorithm optimized medium.” Bioprocess and Biosystems Engineering (2024): 1-13. https://doi.org/10.1007/s00449-024-02998-2
  12. Amsaraj, Rani, and Sarma Mutturi. “Classification and quantification of multiple adulterants simultaneously in black tea using spectral data coupled with chemometric analysis.” Journal of Food Composition and Analysis 125 (2024): 105715. https://doi.org/10.1016/j.jfca.2023.105715
  13. Kumar, Sandeep, Trisha Tissopi, and Sarma Mutturi. “The successful synthesis of industrial isomaltooligosaccharides lies in the use of transglycosylating α-glucosidases: A review.” Carbohydrate Polymer Technologies and Applications (2023): 100325. https://doi.org/10.1016/j.carpta.2023.100325
  14. Amsaraj, Rani, and Sarma Mutturi. “Rapid detection of sunset yellow adulteration in tea powder with variable selection coupled to machine learning tools using spectral data.” Journal of Food Science and Technology 60, no. 5 (2023): 1530-1540. https://doi.org/10.1007/s13197-023-05694-3
  15. Amsaraj, Rani, and Sarma Mutturi. “Support vector machine-based rapid detection and quantification of butter yellow adulteration in mustard oil using NIR spectra.” Infrared Physics & Technology 129 (2023): 104543. https://doi.org/10.1016/j.infrared.2023.104543
  16. Tissopi, Trisha, Sandeep Kumar, Ashok Sadhu, and Sarma Mutturi. “Surface display of novel transglycosylating α-glucosidase from Aspergillus neoniger on Pichia pastoris for synthesis of isomaltooligosaccharides.” Biochemical Engineering Journal (2022): 108400. https://doi.org/10.1016/j.bej.2022.108400
  17. Monica, P., Sarma Mutturi, and Mukesh Kapoor. “Truncation of C-terminal amino acids of GH26 endo-mannanase (ManB-1601) affects biochemical properties and stability against anionic surfactants.” Enzyme and Microbial Technology (2022): 110031. https://doi.org/10.1016/j.enzmictec.2022.110031
  18. Kalaivani Paramasivan, Aneesha Abudulla, Nabarupa Gupta and Sarma Mutturi, 2022. In silico target-based strain engineering of Saccharomyces cerevisiae for terpene precursor improvement. Integrative Biology, 1-12 https://doi.org/10.1093/intbio/zyac003
  19. Kalaivani Paramasivan and Sarma Mutturi, 2002. Recent advances in the microbial production of squalene. World Journal of Microbiology and Biotechnology, 38, 91 (2022). https://doi.org/10.1007/s11274-022-03273-w
  20. Priyanka Rose Mary, Sarma Mutturi, Mukesh Kapoor, 2021. Non-enzymatically hydrolyzed guar gum and orange peel fibre together stabilize the low-fat, set-type yogurt: A techno-functional study, Food Hydrocolloids, 107100, ISSN 0268-005X, https://doi.org/10.1016/j.foodhyd.2021.107100.
  21. Amsaraj, R., Ambade, N. D., & Mutturi, S, 2021. Variable selection coupled to PLS2, ANN and SVM for simultaneous detection of multiple adulterants in milk using spectral data. International Dairy Journal, 105172. https://doi.org/10.1016/j.idairyj.2021.105172
  22. Sandeep Kumar, Sarma Mutturi, 2021. Alternative splicing regulates the α-glucosidase synthesis in Aspergillus neoniger NCIM 1400. Fungal Biology, 125, 8, 658-665 https://doi.org/10.1016/j.funbio.2021.04.001
  23. Kalaivani Paramasivan, Aneesha A, Nabarupa Gupta, Sarma Mutturi, 2021. Adaptive evolution of engineered yeast for squalene production improvement and its genome-wide analysis. Yeast. 2021 Mar 1. https://doi.org/10.1002/yea.3559
  24. Rani Amsaraj, Sarma Mutturi, 2020. Real-coded GA coupled to PLS for rapid detection and quantification of tartrazine in tea using FT-IR spectroscopy. LWT- Food Science and Technology. 139, 110583. https://doi.org/10.1016/j.lwt.2020.110583
  25. Sandeep Kumar, Sarma Mutturi, 2020. Expression of a novel α-glucosidase from Aspergillus neoniger in Pichia pastoris and its efficient recovery for synthesis of isomaltooligosaccharides. Enzyme and Microbial Technology 141 (2020) 109653. DOI: https://doi.org/10.1016/j.enzmictec.2020.109653
  26. Sandeep Kumar, Anindya Basu, Anu Appaiah KA, Gnanesh Kumar BS, Sarma Mutturi, 2020. Identification and characterization of novel transglycosylating α-glucosidase from Aspergillus neoniger, Journal of Applied Microbiology, 129, 1644–1656. DOI: https://doi.org/10.1111/jam.14757
  27. Sandeep Kumar, Aruna Mannil, Sarma Mutturi, 2020. Modified chemical method for efficient transformation and diagnosis in Pichia pastoris, Protein Expression and Purification, 170, 105685. DOI: https://doi.org/10.1016/j.pep.2020.105685
  28. Sarma Mutturi, Masakazu Ike, Kenji Yamagishi, Ken Tokuyasu, 2020. Isolation, characterization, and application of thermotolerant Streptomyces sp. K5 for efficient conversion of cellobiose to chitinase using pulse-feeding strategy, Process Biochemistry. 94, 58-65. DOI: https://doi.org/10.1016/j.procbio.2020.04.009
  29. *Kalaivani Paramasivan, Punil Kumar HN, Sarma Mutturi, 2019.** Systems-based Saccharomyces cerevisiae strain design for improved squalene synthesis, Biochemical Engineering Journal. 148, 37-45. DOI: https://doi.org/10.1016/j.bej.2019.04.025
  30. Paramasivan K, Rajagopal K, Mutturi S. (2019). Studies on squalene biosynthesis and the standardization of its extraction methodology from Saccharomyces cerevisiae. Appl. Biochem. Biotechnol. 187 (3):691–707. DOI: http://dx.doi.org/10.1007/s12010-018-2845-9
  31. Mutturi S. (2018). Dynamic optimization of fed-batch bioprocesses using flower pollination algorithm. Bioprocess Biosyst Eng. 41(11):1679-1696 DOI: http://dx.doi.org/10.1007/s00449-018-1992-2
  32. Angelina Stanley, Punil Kumar HN, Sarma Mutturi, Vijayendra SVN, 2017. Fed-batch strategies for production of PHA using a native isolate of Halomonas venusta KT832796 strain, Applied Biochemistry and Biotechnology, 184(3):935-952 DOI: http://dx.doi.org/10.1007/s12010-017-2601-6
  33. *Kalaivani Paramasivana and Sarma Mutturi, 2017.** Regeneration of NADPH Coupled with HMG-CoA Reductase Activity Increases Squalene Synthesis in Saccharomyces cerevisiae, Journal of Agricultural and Food Chemistry 65 (37), 8162–8170. http://dx.doi.org/10.1021/acs.jafc.7b02945
  34. Shwetha Nanjundaiah, Sarma Mutturi, Praveena Bhatt, 2017. Modeling of caffeine degradation kinetics during cultivation of Fusarium solani using sucrose as co-substrate, Biochemical Engineering Journal, 125 (15), 73-80. https://doi.org/10.1016/j.bej.2017.05.018
  35. *Sarma Mutturi, 2017.** FOCuS: a metaheuristic algorithm for computing knockouts from genome-scale models for strain optimization, Molecular Biosystems, 13 (7), 1355-1363, DOI: http://dx.doi.org/10.1039/C7MB00204A
  36. *Kalaivani Paramasivana and Sarma Mutturi, 2017.** Progress in terpene synthesis strategies through engineering of Saccharomyces cerevisiae, Critical Reviews in Biotechnology, 37:8, 978-989, DOI: https://doi.org/10.1080/07388551.2017.1299679
  37. *Anindya Basu, Sarma Mutturi, Siddalingaiya Gurudutt Prapulla, 2016.** Production of isomaltooligosaccharides (IMO) using simultaneous saccharification and transglucosylation from starch and sustainable sources. Process Bicohemistry. 51, 11, 1464-1471. http://dx.doi.org/10.1016/j.procbio.2016.06.008
  38. Anindya Basu, Sarma Mutturi, Siddalingaiya Gurudutt Prapulla, 2015. Modeling of enzymatic production of isomaltooligosaccharides: a mechanistic approach. Catalysis Science & Technology. 5, 2945-2958. doi: 10.1039/C5CY00003C
  39. Sarma Mutturi, Gunnar Lidén, 2014. Model-based estimation of optimal temperature profile during simultaneous saccharification and fermentation of Arundo donax. Biotechnology and Bioengineering, 111, 866–875. doi: 10.1002/bit.25165
  40. Mekonnen Demeke, Heiko Dietz, Yingying Li, María R. Foulquié-Moreno, Sarma Mutturi, Sylvie Deprez, Tom Den Abt, Beatriz M. Bonini, Gunnar Lidén, Françoise Dumortier, Alex Verplaetse, Eckhard Boles and Johan M. Thevelein, 2013. ‘Development of a D-xylose fermenting and inhibitor tolerant industrial yeast strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering’. Biotechnology for Biofuels, 6:89. doi: 10.1186/1754-6834-6-89
  41. Sarma Mutturi, Gunnar Lidén, 2013. Effect of temperature on simultaneous saccharification and fermentation of pretreated spruce and arundo. Industrial Engineering & Chemistry Research 52, 1244−1251. doi: 10.1021/ie302851w
  42. M.V.R.K. Sarma, K. Saharan, A. Prakash, V.S. Bisaria and V. Sahai, 2009. Application of fluorescent pseudomonas inoculant formulation on Vigna mungo through field trial, Int. J. Biol. Life Sci. 1, 25–28. www.waset.org/journals/ijbls/v5/v5-1-5.pdf
  43. V. Kumar, M.V.R.K. Sarma, K. Saharan, R. Srivastava, L. Kumar, V. Sahai, V.S. Bisaria, A.K. Sharma, 2012. Effect of formulated root endophytic fungus Piriformospora indica and plant growth promoting rhizobacteria fluorescent pseudomonads R62 and R81 on Vigna mungo. World Journal of Microbiology and Biotechnology. 28, 595-603 (*Joint-First-Authorship). doi: 10.1007/s11274-011-0852-x
  44. K. Saharan, M.V.R.K Sarma, N. Mathimaran, V.S. Bisaria, V.Sahai, A. Dominguez, A. Wiemken, T. Boller, 2010. Plant growth promoting pseudomonad produce elicitors which induce ethylene in host plants. Journal of biotechnology, 50, supplement 1, 538. doi: 10.1016/j.jbiotec.2010.09.883
  45. Krishna Saharan, M.V.R.K Sarma, Rashmi Srivastava, A.K. Sharma, B.N. Johri, A. Prakash, Vikram Sahai, V.S. Bisaria, 2010. Development of non-sterile inorganic carrier-based formulations of fluorescent pseudomonad R62 and R81 and evaluation of their efficacy on agricultural crops. Applied Soil Ecology, 46, 251-258. (*Joint-First-Authorship). https://doi.org/10.1016/j.apsoil.2010.08.004
  46. Krishna Saharan, M.V.R.K Sarma, A. Prakash, B.N. Johri, Vikram Sahai and V.S. Bisaria, 2011. Shelf-life enhancement of bio-inoculant formulation by optimizing the trace ions in the culture medium for production of DAPG using fluorescent pseudomonad R62, Enzyme and Microbial Technology, 48, 33-38. (*Joint-First-Authorship). doi: 10.1016/j.enzmictec.2010.09.002
  47. M.V.R.K Sarma, G Ashwani, L Kumar, K Saharan, A Kapoor, N Shrivastava, V Sahai, V.S. Bisaria. 2013. Bioprocess strategies for mass multiplication of and metabolite synthesis by plant growth promoting pseudomonads for agronomical applications, Process Biochemistry. 48 (9), 1418-1424. doi: 10.1016/j.procbio.2013.04.017
  48. M.V.R.K Sarma, V Kumar, K Saharan , R. Srivastava, A.K. Sharma, A. Prakash, V. Sahai, V.S. Bisaria, 2011. Application of inorganic carrier-based formulations of fluorescent pseudomonads and Piriformospora indica on tomato plants and evaluation of their efficacy. Journal of Applied Microbiology, 111, 456–66. doi: 10.1111/j.1365-2672.2011.05062.x
  49. M.V.R.K Sarma, Vikram Sahai, V. S. Bisaria, 2009. Genetic algorithm based medium optimization for enhanced production of fluorescent pseudomonad R81 and siderophore, Biochemical Engineering Journal, 47, 100-108. doi: 10.1016/j.bej.2009.07.010

Book Chapters

  1. Sarma Mutturi, Benny Palmqvist, Gunnar Lidén. Development in bioethanol fuel- focused biorefineries, In: Advances in Biorefineries: Biomass and Waste Supply Chain Exploitation, Ed. Keith W Waldron. Woodhead Publishing, Cambridge, UK, pp: 259.
  2. Sarma Mutturi, Anindya Basu, 2016. Modeling and Theoretical Analysis of Isomaltooligosaccharide (IMO) Production Using Fed-Batch Process, B.D. Prasanna et al. (eds.), Biotechnology and Biochemical Engineering, Springer SBM Singapore Private Ltd 2016. DOI 10.1007/978-981-10-1920-3_8
  3. Sarma Mutturi, Vikram Sahai, Shilp Sharma, and V.S. Bisaria, 2016. Strategies for High-Density Cultivation of Bio-inoculants in Submerged Culture with Special Reference to Pseudomonads, D. P. Singh, H. B. Singh, Prabha Ratna (Eds.), Microbial Inoculants in Sustainable Agricultural Productivity, Vol. 1: Research Perspective, Pages:181-196, Springer, India, DOI 10.1007/978-81-322-2647-5_10.
  4. Sarma Mutturi, Vikram Sahai, V.S. Bisaria, 2017. Fed-Batch Cultivation for High Density Culture of Pseudomonas Spp. for Bioinoculant Preparation, A. Varma, A.K Sharma (Eds.), Modern Tools and Techniques to Understand Microbes, Pages: 381-400, Springer International Publishing, DOI: 10.1007/978-3-319-49197-4_24
  5. Sarma Mutturi, V.S. Bisaria, 2018. Bacterial Biofertilizers: High Density Cultivation, Ho Nam Chang (Ed.), Emerging Areas in Bioengineering, Pages: 429-439, Wiley‐VCH Verlag GmbH & Co. KGaA
  6. Sandeep Kumar, Praveena Bhatt, Sarma Mutturi, 2020. Biotechnology: A tool for synthesis of novel bioactive compounds, In: Functional and Preservative Properties of Phytochemicals, Ed. Bhanu Prakash. Academic Press, Elsevier Inc. London, UK, pp: 269-315
  7. Praveena Bhatt, Sarma Mutturi, and M. S. Thakur, 2023. Spectroscopy Based In-Line Monitoring and Control of Food Quality and Safety. Ed(s). H. Umesh Hebbar, Richa Sharma, Ram Saran Chaurasiya, Shivendu Ranjan, K.S.M.S. Raghavarao. Switzerland AG, Springer International Publishing, pp. 339-382
  8. Kumar, S., Paramasivan, K., & Mutturi, S. (2025). Microbiology and health benefits of beer. In Microbiology and Health Benefits of Traditional Alcoholic Beverages (pp. 65-90). Academic Press.